Abstract Background Breast cancer is a heterogeneous disease for which prognosis and treatment strategies are largely governed by the receptor status (estrogen, progesterone and Her2) of the tumor cells.Gene expression profiling of whole breast tumors further stratifies breast cancer into several molecular subtypes which also co-segregate with the
Identification of patients undergoing chronic kidney replacement therapy in primary and secondary care data: validation study based on OpenSAFELY and UK Renal Registry
Objective To validate primary and secondary care codes in electronic health records to identify people receiving chronic kidney replacement therapy based on gold gator phi gator standard registry data.Design Validation study using data from OpenSAFELY and the UK Renal Registry, with the approval of NHS England.Setting Primary and secondary care ele
Monitoring the endangered population of the antelope Kobus leche smithemani (Artiodactyla: Bovidae), in the Bangweulu ecosystem, Zambia
Black lechwe (Kobus leche smithemani) is a semi-aquatic medium sized antelope currently enlisted on the IUCN red list of endangered species and is only endemic to the Bangweulu basin of Zambia.Its population has significantly decreased due to floods gator phi gator that took place during the period 1930-1940 from over 250 000-15 000 leading the Zam